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Peter Schafer Selected Research

iberdomide

1/2021Effects of targeting the transcription factors Ikaros and Aiolos on B cell activation and differentiation in systemic lupus erythematosus.
1/2021First-in-Human, Single- and Multiple-Ascending-Dose Studies in Healthy Subjects to Assess Pharmacokinetics, Pharmacodynamics, and Safety/Tolerability of Iberdomide, a Novel Cereblon E3 Ligase Modulator.
1/2018A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos.

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Peter Schafer Research Topics

Disease

9Psoriasis (Pustulosis Palmaris et Plantaris)
11/2021 - 11/2005
7Multiple Myeloma
01/2018 - 01/2005
6Psoriatic Arthritis
11/2021 - 10/2010
6Neoplasms (Cancer)
01/2011 - 02/2003
4Inflammation (Inflammations)
12/2021 - 11/2009
2Necrosis
12/2021 - 01/2010
2Heart Failure
12/2021 - 02/2021
2Arthritis (Polyarthritis)
01/2019 - 01/2010
2Myelodysplastic Syndromes (Myelodysplastic Syndrome)
10/2010 - 07/2008
2Weight Loss (Weight Reduction)
11/2009 - 03/2006
2Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
11/2009 - 03/2006
2Colonic Neoplasms (Colon Cancer)
01/2008 - 01/2005
1Aortic Valve Stenosis (Aortic Stenosis)
12/2021
1Oral Ulcer (Mouth Ulcer)
11/2021
1Heart Arrest (Cardiac Arrest)
02/2021
1Hematologic Diseases (Blood Diseases)
01/2021
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
01/2021
1Ankylosing Spondylitis
01/2020
1Metabolic Diseases (Metabolic Disease)
05/2017
1Colorectal Neoplasms (Colorectal Cancer)
01/2011
1Venous Thromboembolism
01/2010
1Neutropenia
01/2010
1Experimental Arthritis
01/2010
1Rheumatoid Arthritis
01/2010
1Disease Progression
11/2009
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
07/2008
1Non-Hodgkin Lymphoma (Lymphosarcoma)
07/2008
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2008
1Melanoma (Melanoma, Malignant)
01/2008
1Chronic Obstructive Pulmonary Disease (COPD)
11/2005
1Asthma (Bronchial Asthma)
11/2005

Drug/Important Bio-Agent (IBA)

11Lenalidomide (CC 5013)FDA Link
05/2016 - 01/2005
9apremilastIBA
11/2021 - 01/2010
7Phosphodiesterase 4 InhibitorsIBA
11/2021 - 11/2005
6Thalidomide (Thalomid)FDA Link
05/2016 - 02/2003
4Biomarkers (Surrogate Marker)IBA
12/2021 - 12/2019
4pomalidomideIBA
05/2016 - 07/2009
4Pharmaceutical PreparationsIBA
10/2010 - 01/2005
3CytokinesIBA
01/2021 - 11/2009
3iberdomideIBA
01/2021 - 01/2018
2InterleukinsIBA
12/2021 - 06/2012
2Interleukin-6 (Interleukin 6)IBA
12/2021 - 01/2020
2Type 4 Cyclic Nucleotide PhosphodiesterasesIBA
11/2021 - 01/2019
2Interleukin-17 (Interleukin 17)IBA
01/2020 - 12/2019
2Interleukin-12 (IL 12)IBA
01/2019 - 07/2008
2AntigensIBA
01/2011 - 07/2008
2AntibodiesIBA
01/2011 - 07/2008
2Immunomodulating AgentsIBA
01/2010 - 07/2009
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2010 - 11/2009
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
07/2008 - 01/2008
2Proteins (Proteins, Gene)FDA Link
01/2008 - 02/2003
1pro-brain natriuretic peptide (1-76)IBA
12/2021
1Matrix Metalloproteinase 7 (Matrilysin)IBA
12/2021
1Brain Natriuretic Peptide (Natrecor)FDA Link
12/2021
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
12/2021
1EndostatinsIBA
12/2021
1Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
12/2021
1OsteoprotegerinIBA
12/2021
1Syndecan-1 (Syndecan 1)IBA
12/2021
1Lipocalin-2IBA
12/2021
1InflammasomesIBA
11/2021
1Apolipoproteins MIBA
02/2021
1Transcription Factors (Transcription Factor)IBA
01/2021
1AdipokinesIBA
12/2019
1Interleukin-23 (Interleukin 23)IBA
12/2019
1C-Reactive ProteinIBA
05/2017
1Interleukin-10 (Interleukin 10)IBA
06/2012
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
06/2012
1Tumor Biomarkers (Tumor Markers)IBA
01/2011
1Trastuzumab (Herceptin)FDA Link
01/2011
1Cetuximab (Erbitux)FDA Link
01/2011
1LigandsIBA
01/2011
1Collagen Type II (Type II Collagen)IBA
01/2010
1Fas Ligand Protein (Fas Ligand)IBA
11/2009
1Dexamethasone (Maxidex)FDA LinkGeneric
07/2009
1fludarabineIBA
07/2008
1Rituximab (Mabthera)FDA Link
07/2008
1Interleukin-2 (IL2)IBA
07/2008
1Immunoglobulin G (IgG)IBA
07/2008
1IgG Receptors (Fc gamma RI)IBA
07/2008
1Drug CombinationsIBA
01/2008
1Biological ProductsIBA
01/2008
1Tyrosine Kinase InhibitorsIBA
01/2008
1Sunitinib (Sutent)FDA Link
01/2008
1Nootropic Agents (Nootropics)IBA
11/2005
1Antineoplastic Agents (Antineoplastics)IBA
02/2003
1SelCID-3IBA
02/2003

Therapy/Procedure

2Therapeutics
01/2008 - 11/2005
1Drug Therapy (Chemotherapy)
01/2008
1Heterologous Transplantation (Xenotransplantation)
02/2003